What You Should Know About Treatment Resistant Depression

There are times when no matter what you do it seems your depression doesn’t seem to get any better. When traditional or common treatments don’t work there are some other options according to the Mayo Clinic.

When people have treatment resistant depression, normal treatments such as medicines and psychotherapy are not enough. Sometimes your symptoms may go away for a while only to reappear and sometimes these treatments do nothing at all. There are times when many options are tried in an effort to see what will help each person’s treatment resistant depression.

Here are a few of the treatments that your doctor may recommend wen normal treatment methods do not help:

• Give the medications that you are on more time. Although these meds generally take up to 8 weeks to work, everyone’s physiology is different and your body may just need some extra time for the meds to have an effect.
• Altering the dosage.
• Switching medsications
• Adding another medication to your current regimen.
• Adding a medication that is generally only used for a different type of condition. This could be anti-anxiety or seizure meds, beta blockers, stimulants, mood stabilizers or even antipsychotics.
• There is also a test that may be run. This is called a cytochrome P450 genotyping test. (CYP450). What this test does is it can tell which medicine is likely to give you side effects. While this test may not be possible in your local hospital, there are national labs that offer it.


This is also known as psychological therapy and at times it can be extremely effective. There are a great number of patients who find good results when they combine a regimen of medicines along with psychotherapy. This type of treatment can assist in identifying underlying issues that may be exacerbating your depression.
If this type of therapy seems to be ineffective then you can talk to your therapist about alternate options. Some of the available types of psychotherapy include but are not limited to:
• Cognitive behavioral therapy addresses things like the feelings, behaviors and thoughts which affect your moods. This can teach you how to pick out and alter negative thinking patterns as well as teach you the skills necessary to respond to all of the challenges in life in a way that is positive.
• Interpersonal psychotherapy is a type of therapy that will focus on trying to resolve issues with relationships that have contributing factors to your depression.
• Family or marital therapy will involve getting your spouse or family members into therapy with you. It will help to get rid of stress in your relationships which can actually lead to relieving the depression.
• Group psychotherapy works for some people while others find it to be a huge waste of time. This is where a group of strangers gets together with a therapist to try to relieve depression.
• Psychodynamic treatment is an approach to counseling that will help in identifying and resolving problems that may be linked to your depression. This is a type of treatment that may take a great deal longer than other types due to how in depth it is.
Rest assured, just because nothing is helping your depression now, that doesn’t mean that there is no help. Work with your doctors and you will get there.